...

Typhoid fever
occurs each year
globally with

9 Million
cases1
~1 Lakh
deaths1
...

Contact.
Consumption.
Contamination.
Typhoid travels route

...

TYPHOID CAN
BE PREVENTED
with clean
water, hygiene
and timely
vaccination1

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to register
your practice as a certified Typhoid Expert Clinic

all about typhoid

Typhoid is an infectious disease which is transmitted via ingestion of contaminated food or water 2

Symptoms of typhoid

appear after an few weeks of
exposure 1

  • Diarrhoea/ constipation
  • Rash
  • High fever
  • High fever
  • High fever
  • High fever

Serious cases may lead to complications or even death1

Typhoid is prevalent across age groups 3,4,5

506.4/100,000 child-years

Infants under 12
months of age

340/100,000 population-year

Children
aged 2-5 years

493/100,000 population-year

Children aged
5-15 years

120/100,000 population-year

People older
than 15 years

know your typhoid risk

Tick the boxes to know your risk score

WHY SHOULD YOU GET a VACCINATED FOR TYPHOID

...

An incidence of typhoid can cost approximately 35% of the average monthly household income6,7

...

Since typhoid cases are treated with antimicrobials, a resistance is developed and thus, prevention by vaccine is of utmost importance8

Vaccination is the most effective way to prevent typhoid and minimise it’s treatment cost

vaccines available

Polysaccharide vaccines (PSV)

have been available for many years, yet a large population remains at higher risk due to the low efficacy of these vaccines, requirement for multiple doses, and restrictive age limit for those below 2 years

Typhoid conjugate vaccines (TCV)

are more efficacious than the previously available polysaccharide vaccines 9,10

Provides long lasting protection

Can be administered to childrenabove 6 months of age

Requires one dose and effective for more than 2 years

Has higher efficacy along with immune memory

TCV is a cost-saving strategy in urban India

WHO SHOULD GET a VACCINATED FOR TYPHOID?
Dose Initiation

ACVIP and WHO recommend TCV from 6 months onwards 11

Vaccine naïve population

It is believed that typhoid vaccine is only for kids aged 6 months. However, any individual above 6 months of age if not vaccinated against typhoid should be vaccinated

Previously vaccinated with polysaccharide vaccine

The new age typhoid vaccines (Typhoid Conjugate Vaccines) are once-in-a-lifetime vaccine that provides long-term protection

Blogs

Review on the Recent Advances on Typhoid Vaccine Development and Challenges Ahead

An overview of the licensed typhoid vaccines and vaccine candidates under development, and the challenges ahead for the introduction.

https://academic.oup.com/cid/article/71/Supplement_2/S141/5877822
Fever in the Returned Pediatric Traveler

-the epidemiology, evaluation, and management of specific travel-related infections.

https://pubmed.ncbi.nlm.nih.gov/34423077/
Human Genetic Variation Influences Enteric Fever Progression

-the development of risk prediction tools, novel therapies as well as strategies toward developing a personalized typhoid vaccine.

https://pubmed.ncbi.nlm.nih.gov/33562108/
Salmonella Typhi Shedding and Household Transmission by Children With Blood Culture-confirmed Typhoid Fever in Vellore, South India

potential concurrent typhoid infections in households in settings with poor water and sanitation.

https://pubmed.ncbi.nlm.nih.gov/35238362/
Comparison of Strategies for Typhoid Conjugate Vaccine Introduction in India: A Cost-Effectiveness Modeling Study

typhoid vaccine strategies should be implemented in India.

https://pubmed.ncbi.nlm.nih.gov/35238367/